Genome-wide association studies (GWAS) usage continues to grow in the discovery and development of disease models; however, they are often restricted to interrogation within predefined European ancestry populations.

In this webinar, speakers from Illumina and GENEWIZ will discuss how low-pass whole genome sequencing (LP-WGS) enables genome-wide variant data generation without pre-defined population limitations. The combination of low-pass sequencing data and imputation has the potential to provide up to 99% accurate variant call detection and identification of SNPs, INDELs, and copy number variants, providing an abundance of data for the money spent.

LP-WGS is a technique for a broad spectrum of applications, such as analysis of complex-trait association studies, calculation of genome-wide polygenic risk scores and identifying copy number alterations from cell-free DNA.

What You'll Learn:

- The science behind LP-WGS technology
- Trade-offs of LP-WGS compared to traditional genotyping arrays and other whole genome or targeted approaches
- Applications of LP-WGS – particularly in liquid biopsy sequencing