About
Join us for an insightful webinar exploring how Raman spectroscopy is used as a Process Analytical Technology (PAT) in bioreactor monitoring and control for cultivated meat production. We will explore how utilizing the Thermo Scientific™ MarqMetrix™ All-In-One Process Raman analyzer together with Thermo Fisher Scientific “Core” chemometric models, allows for real-time, accurate monitoring of critical process parameters (CPPs). This approach helps optimize process conditions and generate uniform product quality.

The speaker will provide an in-depth overview of how Raman spectroscopy works and how it can be easily integrated into a cultivated meat production workflow. The webinar will feature a detailed discussion on how Ivy Farm used Thermo Fisher Scientific chemometric "core" models for real-time monitoring of glucose and lactate, eliminating the need for prior sampling and complex chemometrics. They will showcase how these models, tested across multiple cell lines, media, and process scales, effectively save time, cost, and resources associated with chemometric model development.

The webinar will also provide insights into the transferability of these models across multiple instruments, a key factor in scaling up operations, enhancing their versatility and applicability. We will showcase a real-life case study from cultivated meat production, demonstrating the practical application of Raman spectroscopy and its potential impact on product quality and process efficiency.

Who Should Attend?

Whether you are a researcher, a bioprocess professional, or someone interested in advanced process analytical technologies, this webinar will equip you with valuable knowledge and insights into using Raman spectroscopy. Don't miss this opportunity to learn how to transform your bioprocessing operations.
Presenter
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Nimesh Khadka
Senior Product Applications Specialist | Thermo Fisher Scientific
Nimesh Khadka is a Senior Product Applications Specialist at Thermo Fisher Scientific with specializing in analytical biochemistry, spectroscopy, and chemometrics. Driven by passion of innovation, he is currently leading the way in championing Raman spectroscopy as process analytical technology (PAT) for development of protein and nuclei acids therapeutics.

Nimesh completed his Ph.D at Utah State University with focus in enzymology, spectroscopy, and alternative bioenergy. His postdoctoral training was conducted at Case Western Reserve University, where he dedicated his research to the study of structural biology in biomolecules associated with eye pathologies. This extensive background has provided Nimesh with a deep understanding of the intricacies of biomolecular structures and their applications in various fields. As an active member of the American Chemical Society, Nimesh remains at the forefront of emerging technologies and is committed to driving innovation to meet customer’s need.
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