About
Join us for an insightful webinar on the structural dynamics of the cardiac muscle protein, myosin.

About this webinar:

Dr. Colleen Kelly, a renowned postdoctoral researcher from the Previs Lab at the University of Vermont, will discuss cellular and molecular methods used to study myosin.

Our expert speaker will describe how the combination of Microfluidic Diffusional Sizing (MDS) and fluorescence imaging techniques was utilized to provide evidence of a folded conformation of cytosolic cardiac myosin, further advancing our understanding of its dynamics in vivo. 

By attending this webinar, you will learn:

  • An overview of macromolecular protein dynamics within the heart

  • Approaches used to examine protein dynamics from the cellular to molecular levels

  • The application of adeno-associated viral protein expression (AAV), two-photon imaging, fluorescence recovery after photobleaching (FRAP), and microfluidic diffusional sizing (MDS)
    • Presenters
    1675434589-64b466b76391bbe7
    Dr. Colleen Kelly
    Colleen completed her MS in Chemistry (2016) and PhD in Biochemistry (2020) in the Gage Laboratory at the University of Massachusetts, Lowell. Her studies were focused on developing biophysical techniques to measure protein-protein interactions and to examine the folding of immunoglobulin-like domains in the muscle protein titin.

    During that time, Colleen was also a high school chemistry and biotechnology teacher (10+ years).

    Colleen is currently a second-year postdoc in the Previs Laboratory at the University of Vermont, where she studies mechanisms of contractile protein replacement in the heart. The results will enhance our understanding of cardiac muscle development, heart health, and disease.
    1673360013-dd3eb376a51be921
    Molly Coseno
    Field Application Specialist | Fluidic Analytics
    Molly Coseno, PhD is a Technical Application Specialist representing Fluidic Analytic in the United States
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