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Organoid meets Microelectrode Array (MEA) – Accelerating Drug Discovery and Development

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In this webinar, Dr. Sven Schönecker and Sara Mirsadeghi, MSc, discuss 3D Mesh Microelectrode Arrays (MEA) including new developments and applications.

In today’s fast paced research environment, drug testing, regulatory requirements, and alternative methods are at the forefront of neuroscience research. In this webinar, Dr. Sven Schönecker discusses the latest in 3D Mesh MEA's, its ability for a more true-to-life system for studying organoids, and the versatility of the well-established MEA2100 system from Multi Channel Systems (MCS), an affiliate of Harvard Bioscience (HB).

The main challenge in the brain organoid field is to monitor neural network formation within development and manipulate the synaptic plasticity of mature brain organoids. Indeed, this challenge hinders neuroscientists from achieving all aspects of human brain-on-chip. In this webinar, Sara talks about how growing brain organoids around the electrodes, using Mesh MEA, brings neuroscientists closer to the brain-on-chip inherence.

Who can view: People who attended or registered for the webinar only
Webinar Price: Free
Featured Presenters
Webinar hosting presenter

Sven Schönecker, Ph.D.

Global Product Manager, Multi Channel Systems
Sven has a Diploma in Biology from the University of Tübingen, with a focus on molecular biology and pharmacology and received his Ph.D. in Pharmacology at the same university in cooperation with the Natural and Medical Science Institute. There, he focused on non-invasive extracellular recordings of electrical activity. In 2015, he joined Harvard Bioscience in its Multi-Channel Systems division (MCS). Sven has had several roles in the organization, including being a Sr. Application Scientist, the Application Team Leader for Cellular and Molecular Technologies in EIMEA, and is now the global Product Manager for Multielectrode Arrays (MEA).
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Webinar hosting presenter

Sara Mirsadeghi, M.Sc.

Ph.D. student/Research Assistant
Sara has a Master’s degree in developmental biology with a focus on neuroscience from Royan institute, Iran. After graduation, she joined the electrophysiology lab in the same institution as a research associate, for six years, and now she is a Ph.D. student/research assistant in Hsieh lab, University of Texas at San Antonio. Sara is interested in brain-on-chip research. She grows brain organoids from human-derived pluripotent stem cells and compares the organoids’ spiking activity, neural network formation, burst firing and network maturity by placing them on MEAs, manufactured by Multi-Channel Systems. Her experience successfully compares the electrophysiological properties of different brain organoids, derived from healthy donors as well as patients with congenital epilepsy, employing standard MEAs, 3D-MEAs and newer Mesh-MEAs.
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