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WEBINAR ENDED

Multi-View Light Sheet Microscopy to Track Cell Lineages in Tissue Morphogenesis

About This Webinar

Explore the complex dynamics of cell fate decisions and morphogenesis through 3D time-lapse microscopy, using real user data to advance our understanding of developmental biology.
In this webinar, you will learn:
1. How to use multi-view light sheet microscopy to track cell lineages in vivo during embryonic development
2. Ways to use cell tracking data to form hypotheses on gene regulatory networks influencing pattern emergence during morphogenesis
3. About the unique versatility of the Viventis Deep microscope in studying the development of various species and embryo models

A major question in developmental biology is understanding how cellular fate decisions are regulated precisely in space and time.
Fortunately, we can now begin to observe these processes with modern imaging approaches, which allow the tracking of cell fate decision events and cellular rearrangements by live 3D time-lapse microscopy.

This development is shifting our understanding of pattern formation in development away from static models towards models based on the principles of dynamical systems and statistical mechanics.

Join Dr Andrea Boni for a live demonstration of how light-sheet microscopy is the technique of choice for volumetric live imaging of 3D samples at high speed with minimal phototoxicity.

Follow along with two user examples of how light-sheet microscopy is helping scientists understand the biological process of intestinal and brain organoid development.

After this demo, we will introduce the technology behind the Leica Viventis Deep, which combines dual-view illumination and detection in an open-top configuration.

Andrea will demonstrate how this unique configuration allows easy sample mounting and long-term imaging from small embryos and organoids to large multicellular systems.

Agenda
  • Introduction (5 minutes)
  • 45 min Talking Session
  • 15 min Q&A session
Who can view: Everyone
Webinar Price: Free
Featured Presenters
Webinar hosting presenter
Business Excellence Director
Andrea Boni studied Biotechnology at the San Raffaele University in Milan before moving for his PhD at the EMBL laboratory in Heidelberg (Germany) where he worked on microscopy screening of membrane nuclear protein dynamics. After completing his doctoral work he moved to the lab of Prof. Prisca Liberali at FMI in Basel (Switzerland) to work on light-sheet development and imaging of intestinal organoids. In 2017 Andrea co-founded with Petr Strnad Viventis Microscopy based in Lausanne (Switzerland) where he was responsible of the imaging applications and sales. After the integration of Viventis Microscopy in Leica Microsystems he joined Leica in May 2024 as Business Excellence Director.
Webinar hosting presenter
Sr Apps Specialist ANZ & Business Development Manager
Taryn Guinan joined Leica Microsystems in 2018, where she leverages her technical expertise to support a range of imaging solutions, including advanced widefield, confocal, super-resolution, light sheet microscopy, and image analysis.
Taryn earned her PhD in Engineering (Materials and Analytical Chemistry) from the University of South Australia in 2015. Her doctoral research focused on creating nanostructured porous silicon platforms for mass spectrometry aimed at biomolecule detection and imaging. As a postdoctoral researcher at Monash University, she developed cutting-edge mass spectrometry imaging technologies for detecting drugs, lipids, and various other analytes.
Webinar hosting presenter
Marketing Manager
Hosted By
Leica Microsystems webinar platform hosts Multi-View Light Sheet Microscopy to Track Cell Lineages in Tissue Morphogenesis
Leica Microsystems (SEA) Webinars
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