The glymphatic system is a gliovascular clearance system in the brain. In 2012, researchers demonstrated that tracers injected into the ventricular CSF of mice entered the parenchyma of the brain, and were transported into a small space between the brain capillaries and the astrocytes surrounding them, a pre-lymphatic system. This is a very slow clearance pathway in the CNS, present in most mammals, that facilitates the removal of CNS interstitial fluid, as well as waste products, including amyloid beta proteins that accumulate in pathologies such as Alzheimer’s disease.

The Primo Vascular System (PVS) is a unique biological system shifting medical paradigm. It is a new body system that has a specific anatomical and immunohistochemical signature. This sets it apart from the arteriovenous and lymphatic systems. With immune and endocrine functions, the primo vascular system has been found to play a large role in biological processes, including tissue regeneration, inflammation, and cancer

After Paolo Mascagni in 1787 (Vasorum Lymphaticorum Corporis Humani) two separate teams of researchers, one team at the University of Virginia and one team at the University of Helsinki independently found typical lymph vessels in the brain. These vessels, which line the dural sinuses in the brain, carry lymphatic fluid (and immune cells) toward deep nodes of the neck (cervical lymph nodes). We can postulate that manual activation of the lymph flow in the numerous nodes of the neck may stimulate drainage of CNS fluid and waste products, and facilitate transportation of immune cells/antigen-presenting cells to the nodes.

  • Participant will describe basic anatomy and physiology of the Glymphatic System, and its application to brain pathologies.
  • Participant will describe basic anatomy and physiology of the Primo-Vascular System and its application in cancer.
  • Participant will describe basic anatomy, physiology and drainage of the meningeal lymphatic vessels.
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    National Lymphedema Network
    The National Lymphedema Network’s mission is to empower our community of lymphedema practitioners and patients by providing knowledge, networking opportunities, and interventional resources. We educate clinicians and inspire them to provide world-class care for people with lymphedema.
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    Bruno Chikly
    Bruno Chikly, MD (France), DO (France, It., UK), LMT (AZ), is the director of the Lymph Drainage Therapy (LDT) and Brain curriculi. He received a medal of the Medical Faculty of Paris for his thesis on the lymphatics. He also wrote the first extensive book on the lymphatic system (and lipedema) in North America: Silent Waves, Theory and Practice of Lymph Drainage Therapy.

    He extensively studied osteopathic techniques and other hands-on modalities, both in Europe and the United States, including Manual Lymphatic Therapies, Osteopathy in the Cranial field, Biodynamics program in Osteopathy, CranioSacral therapy, Visceral Manipulation, Mechanical Link, Muscle Energy, Myofascial Release, Neuromuscular Therapy, SomatoEmotional Release, etc. Dr. Chikly, is an international seminar leader, lecturer and writer he is past Adjunct Professor of the Union Institute and University Graduate College (University of Ohio), 2014 Massage Therapist Hall of Fame, recipient of the Albert Nelson Marquis Lifetime Achievement Award (December 2019). Dr Chikly has spoken to numerous medical and health-related groups and to many lymphedema support groups. He lives in Arizona with his wife and teaching partner Alaya Chikly, LMT.