Traditional RNA-Seq produces a representative snapshot of the transcriptional state averaged across all cells, losing the resolution of individual cells and cellular subpopulations. The 10x Genomics Chromium™ has emerged as the leading choice for researchers to identify and fully interrogate cellular subpopulations. In this webinar, we will review how recent advancements of the 10x Genomics Chromium™ system, coupled with GENEWIZ developmental efforts, can benefit the researcher. In addition, we will spotlight the new Single-Cell V(D)J Solution, which can be used in conjunction with single-cell transcriptome profiling to identify pairing of full-length BCR and TCR sequences.