About
Given the current landscape in liver transplantation, with a shift from younger donors to more older, obese, and DCD donors as the sources for human grafts, dynamic organ perfusion preservation strategies have become a priority in this field. In this webinar, experts will discuss the basic science behind the different strategies for liver perfusion preservation and how these strategies may be used to recover, evaluate, and even improve the quality of livers for transplantation.

ILTS would like to thank Bridge to Life for their generous support for the production of this webinar. Bridge to Life has had no influence on the content and full editorial control remains the sole responsibility of ILTS.
WEBINAR ENDED
Agenda
  • Overview on Mechanism of Action and Effects of Hypothermic (Oxygenated) Liver Perfusion (James Guarrera)
  • Overview on Mechanism of Action and Effects of Normothermic Perfusion in Liver Transplantation (Peter Friend)
  • Liver Viability Assessment during Machine Perfusion (Andrea Schlegel)
  • Q&A
Presenters
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James V. Guarrera
James V. Guarrera is a Professor of Surgery and Chief for the Division of Liver Transplantation and Hepatobiliary Surgery at Rutgers, New Jersey Medical School. Dr. Guarrera is acknowledged as an international expert and pioneer in Ex-vivo Machine Preservation of donor organs. He is distinguished as the first to clinically preserve human livers using ex-vivo continuous machine perfusion. The techniques he developed paved the way for ex-vivo liver machine perfusion procedures now being implemented in clinical trials by other groups in North America, Europe, and Asia.
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Peter Friend
Peter Friend is a Professor of Transplantation and Consultant Transplant and HPB Surgeon at the Director Oxford Transplant Centre. His experimental interest is in the application of isolated perfusion of the liver to a number of therapeutic areas.  In particular, perfusion of the liver with oxygenated blood at normal body temperature can allow recovery from damage, extended preservation for transplantation and organ specific delivery of therapy.
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Andrea Schlegel
Dr. Andrea Schlegel is a certified transplant and HPB surgeon, currently working at the Careggi University Hospital in Florence, Italy. Since more than 10 years, her research focus on underlying mechanisms of ischemia/reperfusion injury and protective effects of novel machine perfusion technology.
One of Andrea`s main interests is the development of new markers to predict organ viability during machine perfusion, to enable the safe use of high-risk donor livers, as frequently seen in Switzerland, the United Kingdom and Italy, where she worked recently.
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Marit Kalisvaart
Moderator
Marit Kalisvaart works as a general surgery resident and researcher in HPB surgery and liver transplantation at the Department of Surgery and Organ Transplantation at the University Hospital in Zurich, Switzerland. Marit Kalisvaart is a member of the ILTS Vanguard Committee and topic coordinator of the ILTS DCD & Machine Perfusion Special Interest Group.

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SUPPORTED BY: Bridge to Life
Bridge to Life is a leading supplier of preservation solutions globally with a focus on innovation in organ preservation and machine perfusion. Through a strong focus on collaboration with surgeons and transplant professionals, Bridge to Life continues to explore emerging science and preservation technologies. https://bridgetolife.eu
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