Guido Ferrari MD is Professor of Surgery at Duke University and in the Department Molecular Genetics and Microbiology. He is also affiliated faculty at the Duke Global Health Institute, Duke Human Vaccine Institute, and Honorary Professor at the University of Cape Town Department of Immunology. Since 1995 Dr. Ferrari has been evaluating vaccine-induced cytotoxic T lymphocyte (CTL) and antibody dependent cellular cytotoxic (ADCC) responses for the development of AIDS vaccines. Dr. Ferrari has also been the Director of the Center for AIDS Research Immunology Core and of ADCC core laboratory for the Primate AIDS Vaccine Evaluation Group (PAVEG). He was the first to characterize vaccine-induced cross-clade clade CD8 CTL responses and the difference in class I-restricted epitope recognition between individuals with HIV-1 infection and vaccine recipients. He followed this initial epitope mapping of cellular responses with epitope mapping of ADCC responses to identify the anti-C1C2 epitope as the most recognized epitope by ADCC Ab responses in people living with HIV and vaccine recipients. individuals with HIV.